Shape memory alloy actuatable woven neural probes

Gabriella Shull, Henry Koon, Jay Jia Hu, Julianna Abel, Justin Buschnyj, Suhasa B. Kodandaramaiah

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The ability to sense neural activity using electrodes has allowed scientists to use this information to temporarily restore movement in paralyzed individuals using brain-computer interfaces (BCI). However, current electrodes do not provide chronic recording of the brain due to the inflammatory response of the immune system caused by the large (~ 20 - 80 µm) size of the shanks, and the mechanical mismatch of the shanks relative to the brain. Electrode designs are evolving to use small (< 15 µm) flexible neural probes to minimize inflammatory responses and enable chronic use. However, their flexibility limits the scalability – it is challenging to assemble 3D arrays of such electrodes, to insert the arrays of flexible neural probes into the brain without buckling, and to uniformly distribute them into large areas of the brain. Thus, we created Shape Memory Alloy (SMA) actuated Woven Neural Probes (WNPs). A linear array of 32 flexible insulated microwires were interwoven with SMA wires resulting in an ordered array of parallel electrodes. SMA WNPs were shaped to an initial constricted profile for reliable insertion into a tissue phantom. Following insertion, the SMA wires were used as actuators to unravel the constricted WNP to distribute electrodes across large volumes. We demonstrated that the WNPs could be inserted into the brain without buckling and record neural activity. In separate experiments, we showed that the SMA could mechanically distribute the WNPs via thermally induced actuation. This work thus highlights the potential of actuatable WNPs to be used as a platform for neural recording.

Original languageEnglish (US)
Title of host publicationMechanics and Behavior of Active Materials; Structural Health Monitoring; Bioinspired Smart Materials and Systems; Energy Harvesting; Emerging Technologies
PublisherAmerican Society of Mechanical Engineers (ASME)
ISBN (Electronic)9780791851951
DOIs
StatePublished - Jan 1 2018
EventASME 2018 Conference on Smart Materials, Adaptive Structures and Intelligent Systems, SMASIS 2018 - San Antonio, United States
Duration: Sep 10 2018Sep 12 2018

Publication series

NameASME 2018 Conference on Smart Materials, Adaptive Structures and Intelligent Systems, SMASIS 2018
Volume2

Conference

ConferenceASME 2018 Conference on Smart Materials, Adaptive Structures and Intelligent Systems, SMASIS 2018
CountryUnited States
CitySan Antonio
Period9/10/189/12/18

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  • Cite this

    Shull, G., Koon, H., Hu, J. J., Abel, J., Buschnyj, J., & Kodandaramaiah, S. B. (2018). Shape memory alloy actuatable woven neural probes. In Mechanics and Behavior of Active Materials; Structural Health Monitoring; Bioinspired Smart Materials and Systems; Energy Harvesting; Emerging Technologies (ASME 2018 Conference on Smart Materials, Adaptive Structures and Intelligent Systems, SMASIS 2018; Vol. 2). American Society of Mechanical Engineers (ASME). https://doi.org/10.1115/SMASIS2018-8169