Sex steroid hormones and reproductive disorders: Impact on women's health

Bart C.J.M. Fauser, Joop S.E. Laven, Basil C. Tarlatzis, Kelle H. Moley, Hilary O.D. Critchley, Robert N. Taylor, Sarah L. Berga, Paul G. Mermelstein, Paul Devroey, Luca Gianaroli, Thomas D'Hooghe, Paolo Vercellini, Lone Hummelshoj, Susan Rubin, Angelique J. Goverde, Vincenzo De Leo, Felice Petraglia

Research output: Contribution to journalReview articlepeer-review

21 Scopus citations

Abstract

The role of sex steroid hormones in reproductive function in women is well established. However, in the last two decades it has been shown that receptors for estrogens, progesterone and androgens are expressed in non reproductive tissue /organs (bone, brain, cardiovascular system) playing a role in their function. Therefore, it is critical to evaluate the impact of sex steroid hormones in the pathophysiology of some diseases (osteoporosis, Alzheimer, atherosclerosis). In particular, women with primary ovarian insufficiency, polycystic ovary syndrome, endometriosis and climacteric syndrome may have more health problems and therefore an hormonal treatment may be crucial for these women.

Original languageEnglish (US)
Pages (from-to)702-712
Number of pages11
JournalReproductive Sciences
Volume18
Issue number8
DOIs
StatePublished - Aug 2011

Keywords

  • endometrial diseases
  • endometriosis
  • polycystic ovary syndrome
  • post menopausal syndrome
  • primary ovarian insufficiency
  • sex hormones

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