Sex differences in the hemodynamic responses to mental stress: Effect of caffeine consumption

Noha H. Farag, Andrea S. Vincent, Barbara S. Mckey, Mustafa Al'Absi, Thomas L. Whitsett, William R. Lovallo

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

The effect of caffeine on stress responses was compared in 25 men and 22 women in a 2-week placebo-controlled, double-blind, randomized crossover trial. On each week, participants abstained from all dietary sources of caffeine before undergoing a 6-h laboratory protocol under placebo or caffeine exposure followed by a 30-min mental stressor with blood pressure (BP) and cardiovascular hemodynamic assessments. On the placebo session, men and women showed a significant BP increase to stress, although women had significant cardiac responses whereas men had vascular responses. Caffeine ingestion before stress caused both men and women to have enhanced hemodynamic responses to the stressor associated with an increase in cardiac index and a drop in the peripheral resistance index. Caffeine enhances the cardiovascular fight-or-flight response pattern to stress in men and women.

Original languageEnglish (US)
Pages (from-to)337-343
Number of pages7
JournalPsychophysiology
Volume43
Issue number4
DOIs
StatePublished - Jul 2006

Keywords

  • Blood pressure
  • Caffeine
  • Hemodynamics
  • Sex
  • Stress

Fingerprint Dive into the research topics of 'Sex differences in the hemodynamic responses to mental stress: Effect of caffeine consumption'. Together they form a unique fingerprint.

Cite this