Sex differences in methylation profiles are apparent in medulloblastoma, particularly among SHH tumors

Keyphrases

• Medulloblastoma 100%
• Tumor 100%
• Sex Differences 100%
• Methylation Profile 100%
• Immune Parameters 50%
• COL25A1 50%
• Medulloblastoma Subgroups 50%
• Deconvolution 25%
• Clinical Trials 25%
• Therapeutic Target 25%
• Signaling Pathway 25%
• Receptor Regulation 25%
• Tumor Microenvironment 25%
• Sex-specific 25%
• Path Analysis 25%
• Pediatric Brain Tumor 25%
• Gene Pathway 25%
• Chi-square 25%
• B-value 25%
• Illumina 25%
• Kaplan-Meier Survival Curves 25%
• Autosomes 25%
• Publicly Available 25%
• Sexually Dimorphic 25%
• Cyclin-dependent Kinase 6 (CDK6) 25%
• Patient-specific Therapy 25%
• Survival Disparities 25%
• Worse Prognosis 25%
• TLE1 25%
• Unsupervised Hierarchical Clustering 25%
• Significant Pathways 25%
• DNA Methylation Data 25%
• Tumor Subgroups 25%
• FOXN3 25%
• Methylation Data 25%
• Neurotrophic Receptors 25%
• Molecular Subgroups 25%
• RET Proto-oncogene 25%
• Reactome Pathways 25%
• SHH Medulloblastoma 25%
• RNASEH2C 25%
• MMP16 25%
• PRIM2 25%
• B3GNT1 25%
• Advanced Glycosylation End-product Receptor 25%
• FKBP1B 25%
• NPDC1 25%
• Impact Outcomes 25%
• Differentially Methylated Positions 25%

Biochemistry, Genetics and Molecular Biology

• Methylation 100%
• Sex Differences 100%
• Immunocompetent Cell 50%
• Clinical Trial 25%
• Autosome 25%
• Glycosylation 25%
• DNA Methylation 25%
• Prevalence 25%
• TLE1 25%
• Cell Composition 25%
• FKBP1B 25%
• RET Proto-Oncogene 25%