In healthy individuals, plasma cells originating from the bone marrow produce immunoglobulin molecules composed of two heavy chains and two light chains. There are two types of light chains in humans, kappa and lambda. The chapter provides an overview of the history, utility and interpretation of free light chain (FLC) measurement in plasma cell dyscrasias.
|Original language||English (US)|
|Title of host publication||Plasma Cell Neoplasms|
|Subtitle of host publication||A Morphologic, Cytogenetic and Immunophenotypic Approach|
|Publisher||Springer International Publishing|
|Number of pages||18|
|State||Published - Jan 1 2015|