Serum free light chain analysis

Rajeevan Selvaratnam, Jing Cao, Amy B. Karger

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


In healthy individuals, plasma cells originating from the bone marrow produce immunoglobulin molecules composed of two heavy chains and two light chains. There are two types of light chains in humans, kappa and lambda. The chapter provides an overview of the history, utility and interpretation of free light chain (FLC) measurement in plasma cell dyscrasias.

Original languageEnglish (US)
Title of host publicationPlasma Cell Neoplasms
Subtitle of host publicationA Morphologic, Cytogenetic and Immunophenotypic Approach
PublisherSpringer International Publishing
Number of pages18
ISBN (Electronic)9783319109183
ISBN (Print)9783319109176
StatePublished - Jan 1 2015

Bibliographical note

Publisher Copyright:
© Springer International Publishing Switzerland 2016.


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