Serum calcium fractions in essential hypertensive and matched normotensive subjects

Aaron R. Folsom, Charles L. Smith, Ronald J. Prineas, Richard H. Grimm

Research output: Contribution to journalArticlepeer-review

59 Scopus citations


Concentrations of serum total calcium and serum calcium fractions were compared between 28 hypertensive subjects and 28 race-sex-age-matched normotensive controls. Mean levels of serum total calcium were not different between the two groups. Hypertensive subjects had lower mean serum levels of ultrafilterable calcium (-0.32 mg/dl; p = 0.01), ionized calcium (-0.07 mg/dl; p = 0.09), and complexed calcium (-0.23 mg/dl; p = 0.04) and higher levels of protein-bound calcium ( + 0.36 mg/dl; p = 0.07). Estimated dietary calcium intake was similar in the two groups. These findings add to the evidence that essential hypertension is associated with perturbations in calcium metabolism.

Original languageEnglish (US)
Pages (from-to)11-15
Number of pages5
Issue number1
StatePublished - Jan 1986


  • Blood pressure
  • Dietary calcium
  • Hypertension


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