Serum Beta Hydroxybutyrate Concentrations in Cats with Chronic Kidney Disease, Hyperthyroidism, or Hepatic Lipidosis

L. Gorman, L. C. Sharkey, P. J. Armstrong, K. Little, A. Rendahl

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Background: Ketones, including beta hydroxybutyrate (BHB), are produced in conditions of negative energy balance and decreased glucose utilization. Serum BHB concentrations in cats are poorly characterized in diseases other than diabetes mellitus. Hypothesis: Serum BHB concentrations will be increased in cats with chronic kidney disease (CKD), hyperthyroidism (HT), or hepatic lipidosis (HL). Animals: Twenty-eight client-owned cats with CKD, 34 cats with HT, and 15 cats with HL; 43 healthy cats. Methods: Prospective observational study. Serum BHB concentrations were measured at admission in cats with CKD, HT, and HL, for comparison with a reference interval established using healthy cats. Results of dipstick urine ketone measurement, when available, were compared to BHB measurement. Results: Beta hydroxybutyrate was above the reference interval (

Original languageEnglish (US)
Pages (from-to)611-616
Number of pages6
JournalJournal of Veterinary Internal Medicine
Volume30
Issue number2
DOIs
StatePublished - Mar 1 2016

Keywords

  • Ketonuria
  • Ketosis
  • Metabolism
  • Reference intervals

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't

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