Serum ascorbic acid concentrations in previously unsupplemented greyhounds after administration of a single dose of ascorbic acid intravenously or per os

K. C. Scott, R. C. Hill, D. D. Lewis, R. Gronwall, D. A. Sundstrom, G. L. Jones, J. Harper

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Plasma vitamin C concentrations (mean + SD) were measured after a large (1 g) dose of vitamin C was administered orally or intravenously to each of four trained greyhounds in a randomized cross-over design. Concentrations increased (p < 0.05) for 2 h but returned to baseline by 6 h after supplementation. Peak concentrations were greater (p < 0.01) after intravenous than oral administration (6.1 ± 1.2 vs. 0.54 ± 0.23 mg/dl). This suggests that vitamin C must be administered many times daily to maintain plasma concentrations above normal.

Original languageEnglish (US)
Pages (from-to)222-228
Number of pages7
JournalJournal of Animal Physiology and Animal Nutrition
Volume86
Issue number7-8
DOIs
StatePublished - Sep 3 2002

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