Serum α1-antitrypsin concentration in dogs with panniculitis

Dez Hughes, Michael H. Goldschmidt, Robert J. Washabau, Friedrich Kueppers

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Objective - To measure serum α1-antitrypsin (α1AT) concentration in dogs with histologically confirmed panniculitis to determine whether serum deficiency could cause or exacerbate panniculitis in dogs. Design - Cross-sectional, descriptive study. Animals - 9 dogs (5 with multiple lesions and 4 with solitary lesions). Procedure - Serum samples were obtained by means of cephalic or jugular venipuncture and frozen at -20 C until assayed. Serum α1AT concentration was measured by means of radial gel immunodiffusion. Results - In all dogs, serum α1AT concentration was within the previously established reference range. Clinical Implications - In the small number of dogs studied, panniculitis was not associated with serum α1AT deficiency.

Original languageEnglish (US)
Pages (from-to)1582-1584
Number of pages3
JournalJournal of the American Veterinary Medical Association
Issue number9
StatePublished - Nov 1 1996


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