Seroprevalence of Histoplasmosis in Somali, Burmese, and Hmong Refugees Residing in Thailand and Kenya

Nathan C. Bahr, Deborah Lee, William M. Stauffer, Michelle Durkin, Martin S. Cetron, L. Joseph Wheat, David R. Boulware

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Histoplasmosis is known to be endemic to the Midwestern United States, but cases have been reported throughout much of the world. Somali, Hmong, and Burmese (ethnically Karen) persons make up some of the largest refugee populations coming the United States in recent years. Yet, information about risk of Histoplasma capsulatum infection amongst these populations is limited. This study used the CDC Migrant Serum Bank to test ~100 samples from each of Somali, Burmese, and Hmong U.S.-bound refugees. Samples were tested by enzyme immunoassay for Histoplasma capsulatum IgG. Overall 1% (2/299) of refugee serum samples were positive for H. capsulatum IgG. One of 99 samples obtained from Hmong refugees was positive, and the other positive sample came from among 100 Burmese refugee samples. H capsulatum IgG positivity was detected at low levels in Hmong and Burmese refugees. No IgG positivity was detected among 100 Somali refugees.

Original languageEnglish (US)
Pages (from-to)334-338
Number of pages5
JournalJournal of Immigrant and Minority Health
Volume20
Issue number2
DOIs
StatePublished - Apr 1 2018

Bibliographical note

Funding Information:
Funding This work was supported by the National Institute of Neurologic Diseases and Stroke (NINDS), National Institute of Allergy and Infectious Diseases (NIAID), and Fogarty International Center (R01NS086312, R25TW009345, T32AI055433).

Funding Information:
The authors thank the laboratory staff at MiraVista diagnostics for sample testing and the staff at the CDC Migrant Serum Bank for sample retrieval. This work was supported by the National Institute of Neurologic Diseases and Stroke (NINDS), National Institute of Allergy and Infectious Diseases (NIAID), and Fogarty International Center (R01NS086312, R25TW009345, T32AI055433). Authors Durkin and Wheat are employees of MiraVista Diagnostics.

Keywords

  • Histoplasma capsulatum
  • Refugee
  • Refugee health
  • Seroepidemiologic studies

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