Serologic profiling and vaccination timing for Lawsonia intracellularis

D. Walter, C. Gebhart, J. Kroll, J. T. Holck, W. Chittick

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


Proper use of available antemortem serologic tests can confirm the need, and allow more precise scheduling, for L intracellularis vaccination. Vaccination should be scheduled for a time at least 8 weeks before observed seroconversion due to natural exposure. Vaccination is often more appropriately scheduled in the nursery phase of production (eg, 5 to 8 weeks of age) rather than in the finishing phase. Lawsonia intracellularis serology cannot reliably be used as a tool for monitoring vaccination compliance or to differentiate seroconversion due to field infection or vaccination. Patterns of antibiotic usage in seroprofiled populations should be recorded and taken into account when results are interpreted, because administration of antibiotics may inhibit L intracellularis seroconversion.

Original languageEnglish (US)
Pages (from-to)310-313
Number of pages4
JournalJournal of Swine Health and Production
Issue number6
StatePublished - Nov 1 2004


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