Sequence-encoded self-assembly of multiple-nanocomponent arrays by 2D DNA scaffolding

Yariv Y. Pinto, John D. Le, Nadrian C. Seeman, Karin Musier-Forsyth, T. Andrew Taton, Richard A. Kiehl

Research output: Contribution to journalArticlepeer-review

177 Scopus citations

Abstract

Regular 2D arrays of multiple types of nanocomponents were constructed by self-assembly to DNA scaffolding with alternating rows of sequence-encoded hybridization sites. Different-sized Au particles coated with DNA complementary to one of the sites were bound to the scaffolding, producing alternating rows of the two nanocomponents with a 32-nm inter-row spacing. These results demonstrate the potential for using DNA to self-assemble complex arrays of components with nanometer-scale precision.

Original languageEnglish (US)
Pages (from-to)2399-2402
Number of pages4
JournalNano letters
Volume5
Issue number12
DOIs
StatePublished - Dec 2005

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