Sensory-predominant, painful, idiopathic neuropathy: Inflammatory changes in sural nerves

Praful Kelkar, Wendy R. McDermott, Gareth J Parry

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Sensory-predominant, painful, idiopathic neuropathies are a common clinical problem. In this retrospective study of 11 patients with such a neuropathy, we found axonal loss in 9, with multifocal axonal loss in 4 patients; there were large perivascular mononuclear inflammatory infiltrates (>50 cells) in 4 and smaller infiltrates (10-20 cells) in 4. These findings suggest that some cases of this neuropathy may be due to autoimmune vasculopathy and therefore may respond to immunotherapy.

Original languageEnglish (US)
Pages (from-to)413-416
Number of pages4
JournalMuscle and Nerve
Volume26
Issue number3
DOIs
StatePublished - Sep 1 2002

Keywords

  • Cryptogenic neuropathy
  • Idiopathic painful neuropathy
  • Idiopathic sensory neuropathy
  • Inflammatory neuropathy

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