Sensory neuropathy with low-dose pyridoxine

Gareth J. Parry, Dale E. Bredesen

Research output: Contribution to journalArticlepeer-review

144 Scopus citations

Abstract

We describe 16 patients with neuropathy associated with pyridoxine abuse. The clinical picture of a pure sensory central-peripheral distal axonopathy was consistent. Pyridoxine dose was 0.2 to 5 g/d, and duration of consumption before symptoms was inversely proportional to the daily intake. In all patients with adequate follow-up, improvement followed discontinuation of pyridoxine. The ready availability of up to 1-gram tablets makes it likely that this neuropathy will continue to be seen.

Original languageEnglish (US)
Pages (from-to)1466-1468
Number of pages3
JournalNeurology
Volume35
Issue number10
DOIs
StatePublished - Oct 1985

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