Bibliographical noteFunding Information:
This work was supported by the UK National Institute for Health Research comprehensive Biomedical Research Centre award to Guy's and St. Thomas' NHS Foundation Trust , in partnership with the King’s College London and King’s College Hospital NHS Foundation Trust. We acknowledge Hsing-San Yang, Cheng-Lin Wu, Wan-Rung Chen, and Hui-Min Su for technical assistance and clinical sample collection. We would also like to thank the patients and their relatives who kindly contributed samples.
Copyright 2019 Elsevier B.V., All rights reserved.