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Self-class I MHC molecules support survival of naive CD8 T cells, but depress their functional sensitivity through regulation of CD8 expression levels
Kensuke Takada,
Stephen C. Jameson
Laboratory Medicine and Pathology
Cancer Immunology
Research output
:
Contribution to journal
›
Article
›
peer-review
70
Scopus citations
Overview
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Dive into the research topics of 'Self-class I MHC molecules support survival of naive CD8 T cells, but depress their functional sensitivity through regulation of CD8 expression levels'. Together they form a unique fingerprint.
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Keyphrases
Complex Molecules
100%
Expression Level
100%
Naïve CD8 T Cell
100%
CD8 Expression
100%
Functional Sensitivity
100%
Major Histocompatability Complex
100%
T Cell Activation
28%
T Cell Survival
28%
CD-8
28%
CD8+ T Cells
14%
Bone Marrow
14%
Deprivation
14%
High Affinity
14%
Naïve T Cells
14%
Lymphopenia
14%
Self-assembling Peptide
14%
Radiosensitive
14%
Enhanced Sensitivity
14%
Long-term Survival
14%
Transcriptional Mechanism
14%
Dynamic Tuning
14%
Cell Sensitivity
14%
Radioresistant Cells
14%
Complex Expressions
14%
Naïve T Cell Homeostasis
14%
Affinity Peptide
14%
CD4 T Cells
14%
Immunology and Microbiology
Cytotoxic T-Cell
100%
CD8
100%
Cell Survival
33%
Naive T Cell
33%
T-Helper Cell
16%
Cell Function
16%
Homeostasis
16%
Long Term Survival
16%
Lymphocytopenia
16%