@article{74dc0420fbd9478bb175faf707efd7d7,
title = "Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer",
abstract = "Background: The androgen receptor (AR) is a transcription factor regulating progression of prostate cancer.Results: Developed compounds inhibit AR transcriptional activity in vitro and in vivo by selective targeting of the AR-DNA-binding domain (DBD).Conclusion: By targeting the DBD, the compounds differ from conventional anti-androgens.Significance: Anti-androgens with a novel mechanism of action have the potential to treat recurrent prostate cancer.",
author = "Kush Dalal and Mani Roshan-Moniri and Aishwariya Sharma and Huifang Li and Fuqiang Ban and Mohamed Hessein and Michael Hsing and Kriti Singh and Eric LeBlanc and Scott Dehm and {Tomlinson Guns}, {Emma S.} and Artem Cherkasov and Rennie, {Paul S.}",
note = "Publisher Copyright: {\textcopyright} 2014 by The American Society for Biochemistry and Molecular Biology, Inc. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.",
year = "2014",
month = sep,
day = "19",
doi = "10.1074/jbc.M114.553818",
language = "English (US)",
volume = "289",
pages = "26417--26429",
journal = "Journal of Biological Chemistry",
issn = "0021-9258",
publisher = "American Society for Biochemistry and Molecular Biology Inc.",
number = "38",
}