Selective Csp2-Csp bond cleavage: The nitrogenation of alkynes to amides

Chong Qin; Peng Feng; Yang Ou; Tao Shen; Teng Wang; Ning Jiao

doi:10.1002/anie.201303376

Selective C_sp²-C_sp bond cleavage: The nitrogenation of alkynes to amides

Chong Qin, Peng Feng, Yang Ou, Tao Shen, Teng Wang, Ning Jiao

Research output: Contribution to journal › Article › peer-review

85 Scopus citations

Abstract

Breakthrough: A novel catalyzed direct highly selective C sp 2-C _sp bond functionalization of alkynes to amides has been developed. Nitrogenation is achieved by the highly selective C sp 2-C_sp bond cleavage of aryl-substituted alkynes. The oxidant-free and mild conditions and wide substrate scope make this method very practical.

Original language	English (US)
Pages (from-to)	7850-7854
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	52
Issue number	30
DOIs	https://doi.org/10.1002/anie.201303376
State	Published - Jul 22 2013
Externally published	Yes

Keywords

C-C bond cleavage
alkynes
amides
gold
rearrangement

Publisher link

10.1002/anie.201303376

Find It

Find It at U of M Libraries

Cite this

@article{4a3fc45d46414897a5793111efb51ac8,

title = "Selective Csp2-Csp bond cleavage: The nitrogenation of alkynes to amides",

abstract = "Breakthrough: A novel catalyzed direct highly selective C sp 2-C sp bond functionalization of alkynes to amides has been developed. Nitrogenation is achieved by the highly selective C sp 2-Csp bond cleavage of aryl-substituted alkynes. The oxidant-free and mild conditions and wide substrate scope make this method very practical.",

keywords = "C-C bond cleavage, alkynes, amides, gold, rearrangement",

author = "Chong Qin and Peng Feng and Yang Ou and Tao Shen and Teng Wang and Ning Jiao",

year = "2013",

month = jul,

day = "22",

doi = "10.1002/anie.201303376",

language = "English (US)",

volume = "52",

pages = "7850--7854",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "30",

}

TY - JOUR

T1 - Selective Csp2-Csp bond cleavage

T2 - The nitrogenation of alkynes to amides

AU - Qin, Chong

AU - Feng, Peng

AU - Ou, Yang

AU - Shen, Tao

AU - Wang, Teng

AU - Jiao, Ning

PY - 2013/7/22

Y1 - 2013/7/22

N2 - Breakthrough: A novel catalyzed direct highly selective C sp 2-C sp bond functionalization of alkynes to amides has been developed. Nitrogenation is achieved by the highly selective C sp 2-Csp bond cleavage of aryl-substituted alkynes. The oxidant-free and mild conditions and wide substrate scope make this method very practical.

AB - Breakthrough: A novel catalyzed direct highly selective C sp 2-C sp bond functionalization of alkynes to amides has been developed. Nitrogenation is achieved by the highly selective C sp 2-Csp bond cleavage of aryl-substituted alkynes. The oxidant-free and mild conditions and wide substrate scope make this method very practical.

KW - C-C bond cleavage

KW - alkynes

KW - amides

KW - gold

KW - rearrangement

UR - http://www.scopus.com/inward/record.url?scp=84880395260&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84880395260&partnerID=8YFLogxK

U2 - 10.1002/anie.201303376

DO - 10.1002/anie.201303376

M3 - Article

C2 - 23804537

AN - SCOPUS:84880395260

SN - 1433-7851

VL - 52

SP - 7850

EP - 7854

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 30

ER -