TY - JOUR
T1 - Sedentary Behavior, Physical Activity, and Abdominal Adipose Tissue Deposition
AU - Whitaker, Kara M.
AU - Pereira, Mark A
AU - Jacobs Jr, David R
AU - Sidney, Stephen
AU - Odegaard, Andrew O.
N1 - Publisher Copyright:
© Copyright 2017 by the American College of Sports Medicine.
PY - 2017/3/1
Y1 - 2017/3/1
N2 - Purpose We examined whether sedentary lifestyle habits and physical activity level are associated with abdominal visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), intermuscular adipose tissue (IMAT), and liver attenuation, independently of one another and potential confounders. Methods This study analyzed 3010 African American and Caucasian men and women, 42-59 yr old, from the Coronary Artery Risk Development in Young Adults (CARDIA) study, who completed multiple-slice abdominal computed tomography in 2010-2011. Participants reported average hours per day sitting (television, computing, paperwork, music, telephone, and car). Physical activity was assessed with the CARDIA physical activity history. VAT, SAT, IMAT, and liver attenuation were estimated from computed tomography. Multivariable general linear regression models regressed means of fat depots on total sedentary time, task-specific sedentary time, and total physical activity. Results Television viewing was positively, and physical activity inversely, associated with fat depots. For each 1 SD increment in television viewing (1.5 h·d -1), VAT, SAT, and IMAT were greater by 3.5, 3.4, and 3.9 cm 3, respectively (P < 0.03 for all). For each 1 SD increment in physical activity (275 exercise units), VAT, SAT, and IMAT were lower by 7.6, 6.7, and 8.1 cm 3, respectively, and liver attenuation was greater (indicating more liver fat) by 0.5 Hounsfield units (P < 0.01 for all). Total sedentary time was associated with VAT, IMAT, and liver attenuation in White men only after controlling for physical activity, SAT, and other potential confounders (P ≤ 0.01 for all). No other task-specific sedentary behaviors were associated with fat depots. Conclusions Sedentary behaviors, particularly television viewing, and physical activity levels have distinct, independent associations with fat deposition.
AB - Purpose We examined whether sedentary lifestyle habits and physical activity level are associated with abdominal visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), intermuscular adipose tissue (IMAT), and liver attenuation, independently of one another and potential confounders. Methods This study analyzed 3010 African American and Caucasian men and women, 42-59 yr old, from the Coronary Artery Risk Development in Young Adults (CARDIA) study, who completed multiple-slice abdominal computed tomography in 2010-2011. Participants reported average hours per day sitting (television, computing, paperwork, music, telephone, and car). Physical activity was assessed with the CARDIA physical activity history. VAT, SAT, IMAT, and liver attenuation were estimated from computed tomography. Multivariable general linear regression models regressed means of fat depots on total sedentary time, task-specific sedentary time, and total physical activity. Results Television viewing was positively, and physical activity inversely, associated with fat depots. For each 1 SD increment in television viewing (1.5 h·d -1), VAT, SAT, and IMAT were greater by 3.5, 3.4, and 3.9 cm 3, respectively (P < 0.03 for all). For each 1 SD increment in physical activity (275 exercise units), VAT, SAT, and IMAT were lower by 7.6, 6.7, and 8.1 cm 3, respectively, and liver attenuation was greater (indicating more liver fat) by 0.5 Hounsfield units (P < 0.01 for all). Total sedentary time was associated with VAT, IMAT, and liver attenuation in White men only after controlling for physical activity, SAT, and other potential confounders (P ≤ 0.01 for all). No other task-specific sedentary behaviors were associated with fat depots. Conclusions Sedentary behaviors, particularly television viewing, and physical activity levels have distinct, independent associations with fat deposition.
KW - INTERMUSCULAR ADIPOSE TISSUE
KW - LIVER ATTENUATION
KW - SUBCUTANEOUS ADIPOSE TISSUE
KW - VISCERAL ADIPOSE TISSUE
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U2 - 10.1249/MSS.0000000000001112
DO - 10.1249/MSS.0000000000001112
M3 - Article
C2 - 27749387
AN - SCOPUS:84991454177
SN - 0195-9131
VL - 49
SP - 450
EP - 458
JO - Medicine and science in sports and exercise
JF - Medicine and science in sports and exercise
IS - 3
ER -