The Coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has significantly impacted global health and healthcare delivery systems. To characterize the secondary effects of the COVID-19 pandemic and mitigation strategies used in the delivery of hematopoietic stem cell transplantation (HSCT) care, we performed a comprehensive literature search encompassing changes in specific donor collection, processing practices, patient outcomes, and patient-related concerns specific to HSCT and HSCT-related healthcare delivery. In this review, we summarize the available literature on the secondary impacts the COVID-19 pandemic on the fields of HSCT and cellular therapy. The COVID-19 pandemic has had numerous secondary impacts on patients undergoing HSCT and the healthcare delivery systems involved in providing complex care to HSCT recipients. Institutions must identify these influences on outcomes and adjust accordingly to maintain and improve outcomes for the transplantation and cellular therapy community.
|Original language||English (US)|
|Number of pages||10|
|Journal||Transplantation and Cellular Therapy|
|State||Published - Nov 2022|
Bibliographical noteFunding Information:
Financial disclosure: S.R. received support from the National Center for Advancing Translational Sciences (2KL2TR002547; Raed Dweik, principal investigator). Conflict of interest statement: R.P. reports serving on an advisory board for bluebird bio and receipt of research funding from Amgen. C.D. reports honoraria from Omeros and Alexion Pharmaceuticals. The other authors have no conflicts of interest to report. Financial disclosure: See Acknowledgments on page XXX.
Financial disclosure: S.R. received support from the National Center for Advancing Translational Sciences (2KL2TR002547; Raed Dweik, principal investigator).
© 2022 The American Society for Transplantation and Cellular Therapy
- Cell therapy
- Healthcare delivery
- Hematopoietic stem cell transplantation
- Mitigation strategies
- Severe acute respiratory syndrome
PubMed: MeSH publication types
- Journal Article
- Research Support, N.I.H., Extramural