Screening for Colorectal Cancer

David A. Ahlquist, Charles G. Moertel, Douglas B. Mcgill, William D. Carey, Edgar Achkar, Robert Perlman, Brian Budenholzer, Alfred I. Neugut, Judith S. Jacobson, James E. Allison, Martin L. Brown, Jack S. Mandel, Timothy R. Church, Fred Ederer, Sidney J. Winawer

Research output: Contribution to journalLetterpeer-review

12 Scopus citations


To the Editor: We have three questions about the important fecal occult-blood screening study by Mandel et al. (May 13 issue)1. First, although mortality from colorectal cancer was significantly reduced in the annually screened group, it is not clear whether this gain can be attributed to the selective detection of cancer by screening or to an artifact of the very high rate of false positive results (occurring in 10 percent of those screened each year) and consequent numerous colonoscopies. According to the authors' data, about 10,000 colonoscopies or colorectal examinations were performed in this group of about 15,000 to…

Original languageEnglish (US)
Pages (from-to)1351-1354
Number of pages4
JournalNew England Journal of Medicine
Issue number18
StatePublished - Oct 28 1993


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