Scarce but scary

Anja Katrin Bielinsky

Research output: Contribution to journalShort surveypeer-review

2 Scopus citations

Abstract

Spontaneous, replication-induced DNA breaks are likely to be a primary source of chromosomal rearrangements typical of cancer, but it is unknown how often these breaks occur in normal cells. A new study suggests that they are exceedingly rare but probably up to 100-fold more potent in causing genome instability than previously estimated.

Original languageEnglish (US)
Pages (from-to)707-708
Number of pages2
JournalNature Genetics
Volume39
Issue number6
DOIs
StatePublished - Jun 2007

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