Abstract
Spontaneous, replication-induced DNA breaks are likely to be a primary source of chromosomal rearrangements typical of cancer, but it is unknown how often these breaks occur in normal cells. A new study suggests that they are exceedingly rare but probably up to 100-fold more potent in causing genome instability than previously estimated.
Original language | English (US) |
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Pages (from-to) | 707-708 |
Number of pages | 2 |
Journal | Nature Genetics |
Volume | 39 |
Issue number | 6 |
DOIs | |
State | Published - Jun 2007 |