Scanning Tissue Oxygen Needle Probe

S. Ashkenazi, D. Cho, C. W. Song

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

A new device designed to scan oxygen partial pressure along a line in a biological tissue is described in this paper. The probe is housed in a stainless-steel needle. As opposed to other devices for oxygen scanning in tissue, the new probe does not require mechanical translation of the needle in the tissue. The probe includes an active sensing area along the needle shaft that can be scanned optically by an internal optical fiber. This feature allows for repeated scans of tissue oxygen along a line without translating the needle with respect to the tissue, thus avoiding tissue damage associated with needle motion. First, we describe the design of the device including its sensing mechanism, mechanical design, optical configuration, and signal processing. We then move on to describe the results of the device characterization and testing. Finally, we conclude by discussing possible applications of the device in research and in clinical diagnoses and treatment monitoring.

Original languageEnglish (US)
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer
Pages51-55
Number of pages5
Volume1269
DOIs
StatePublished - 2021

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1269
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Bibliographical note

Publisher Copyright:
© 2021, Springer Nature Switzerland AG.

Keywords

  • Oxygen sensor
  • Phosphorescence
  • Tissue oxygen scanning
  • pO profile
  • Oxygen
  • Signal Processing, Computer-Assisted
  • Needles

PubMed: MeSH publication types

  • Journal Article

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