Sample size and power for pair‐matched case‐control studies

John E. Connett, Judith A. Smith, Richard B. McHugh

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


A new sample size formula is derived herein for matched‐pair case‐control studies. This result is based on an unconditional approach to the use of McNemar's statistic. We contrast this method for determining sample size and power with Schlesselman's conditional approach and compare the results numerically in a Monte Carlo study.

Original languageEnglish (US)
Pages (from-to)53-59
Number of pages7
JournalStatistics in Medicine
Issue number1
StatePublished - Jan 1 1987


  • Matched pairs
  • Power Case‐control design
  • Sample size


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