TY - JOUR
T1 - Safety and Outcomes of Capsule Endoscopy in Patients with Left Ventricular Assist Device
T2 - a Single-Center Retrospective Case Series
AU - Hanson, Brian J.
AU - Koene, Ryan J.
AU - Roy, Samit S.
AU - Eckman, Peter M.
AU - John, Ranjit
AU - Chaudhary, Nadeem A.
AU - Vega-Peralta, Jose
N1 - Publisher Copyright:
© 2016, Springer Science+Business Media New York.
PY - 2016/8/1
Y1 - 2016/8/1
N2 - Obscure gastrointestinal bleeding (GIB) in patients with continuous-flow left ventricular assist devices (CF-LVAD) is common. Capsule endoscopy (CE) can be used in the diagnosis of obscure GIB. Safety and outcomes of CE in patients with CF-LVAD are unknown. The aim is to define the safety and outcomes of CE in this population. Paitents with CF-LVAD undergoing CE at a single center between 2007 and 2014 were retrospectively reviewed. Thirty-four CE studies were performed. Positive CE occurred in 19 studies. No clinically significant cardiac events occurred. Medical intervention was the most common management strategy. Rebleeding after CE occurred in 10 patients. Patients with active bleeding or lesions such as arteriovenous malformations (AVM) incurred a higher risk of rebleeding, transfusion, and repeated endoscopy. CE is safe in patients with CF-LVAD. The risk of rebleeding was more common in patients with active bleeding or AVM lesions although this result did not reach statistical significance.
AB - Obscure gastrointestinal bleeding (GIB) in patients with continuous-flow left ventricular assist devices (CF-LVAD) is common. Capsule endoscopy (CE) can be used in the diagnosis of obscure GIB. Safety and outcomes of CE in patients with CF-LVAD are unknown. The aim is to define the safety and outcomes of CE in this population. Paitents with CF-LVAD undergoing CE at a single center between 2007 and 2014 were retrospectively reviewed. Thirty-four CE studies were performed. Positive CE occurred in 19 studies. No clinically significant cardiac events occurred. Medical intervention was the most common management strategy. Rebleeding after CE occurred in 10 patients. Patients with active bleeding or lesions such as arteriovenous malformations (AVM) incurred a higher risk of rebleeding, transfusion, and repeated endoscopy. CE is safe in patients with CF-LVAD. The risk of rebleeding was more common in patients with active bleeding or AVM lesions although this result did not reach statistical significance.
KW - Arteriovenous malformations
KW - Capsule endoscopy
KW - Gastrointestinal hemorrhage
KW - Heart-assist devices
KW - Medical device safety
UR - http://www.scopus.com/inward/record.url?scp=84973131536&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84973131536&partnerID=8YFLogxK
U2 - 10.1007/s12265-016-9701-5
DO - 10.1007/s12265-016-9701-5
M3 - Article
C2 - 27250722
AN - SCOPUS:84973131536
SN - 1937-5387
VL - 9
SP - 402
EP - 404
JO - Journal of cardiovascular translational research
JF - Journal of cardiovascular translational research
IS - 4
ER -