ROLE OF POLYMER MATRIX STRUCTURE AND INTERPARTICLE INTERACTIONS IN DIFFUSION LIMITED DRUG RELEASE.

Anna C. Balazs; Daniel F. Calef; J. M. Deutch; Ronald A. Siegel; Robert Langer

ROLE OF POLYMER MATRIX STRUCTURE AND INTERPARTICLE INTERACTIONS IN DIFFUSION LIMITED DRUG RELEASE.

Anna C. Balazs, Daniel F. Calef, J. M. Deutch, Ronald A. Siegel, Robert Langer

Pharmaceutics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

This investigation used a lattice random walk model to simulate diffusion in a porous polymer, and analyzed the effect of some parameters of the polymer matrix structure, such as the length and width of the connecting constrictions, which contribute to the slowness of the transient kinetics. This model has the advantage of allowing one to consider the complicated geometries involved, as well as incorporating the nonsteady state aspect of this problem.

Original language	English (US)
Title of host publication	Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Material
Publisher	ACS
Pages	47-51
Number of pages	5
Volume	51
State	Published - Dec 1 1984

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ROLE OF POLYMER MATRIX STRUCTURE AND INTERPARTICLE INTERACTIONS IN DIFFUSION LIMITED DRUG RELEASE. / Balazs, Anna C.; Calef, Daniel F.; Deutch, J. M. et al.
Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Material. Vol. 51 ACS, 1984. p. 47-51.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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title = "ROLE OF POLYMER MATRIX STRUCTURE AND INTERPARTICLE INTERACTIONS IN DIFFUSION LIMITED DRUG RELEASE.",

abstract = "This investigation used a lattice random walk model to simulate diffusion in a porous polymer, and analyzed the effect of some parameters of the polymer matrix structure, such as the length and width of the connecting constrictions, which contribute to the slowness of the transient kinetics. This model has the advantage of allowing one to consider the complicated geometries involved, as well as incorporating the nonsteady state aspect of this problem.",

author = "Balazs, {Anna C.} and Calef, {Daniel F.} and Deutch, {J. M.} and Siegel, {Ronald A.} and Robert Langer",

year = "1984",

month = dec,

day = "1",

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AU - Balazs, Anna C.

AU - Calef, Daniel F.

AU - Deutch, J. M.

AU - Siegel, Ronald A.

AU - Langer, Robert

PY - 1984/12/1

Y1 - 1984/12/1

N2 - This investigation used a lattice random walk model to simulate diffusion in a porous polymer, and analyzed the effect of some parameters of the polymer matrix structure, such as the length and width of the connecting constrictions, which contribute to the slowness of the transient kinetics. This model has the advantage of allowing one to consider the complicated geometries involved, as well as incorporating the nonsteady state aspect of this problem.

AB - This investigation used a lattice random walk model to simulate diffusion in a porous polymer, and analyzed the effect of some parameters of the polymer matrix structure, such as the length and width of the connecting constrictions, which contribute to the slowness of the transient kinetics. This model has the advantage of allowing one to consider the complicated geometries involved, as well as incorporating the nonsteady state aspect of this problem.

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M3 - Conference contribution

AN - SCOPUS:0021582359

VL - 51

SP - 47

EP - 51

BT - Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Material

PB - ACS

ER -

ROLE OF POLYMER MATRIX STRUCTURE AND INTERPARTICLE INTERACTIONS IN DIFFUSION LIMITED DRUG RELEASE.

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