Role of amiodarone in the treatment of fetal supraventricular tachyarrhythmias and hydrops fetalis

A. Khositseth, K. D. Ramin, P. W. O'Leary, C. J. Porter

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

We report three consecutive hydropic fetuses with fetal tachyarrhythmias treated with amiodarone - two in combination with digoxin and one with digoxin, procainamide, and propranolol. Sinus rhythm was achieved in one case and ventricular rate control was achieved in two cases. All fetuses treated with amiodarone gradually improved. Observed side effects of amiodarone were a maternal rash in one mother and transient neonatal hypothyroidism in one infant. We conclude that amiodarone might be effective and safe for fetal tachyarrhythmias and impending hydrops. The small number of patients suggests that a multicenter cooperative approach is required in order to determine if this is correct.

Original languageEnglish (US)
Pages (from-to)454-456
Number of pages3
JournalPediatric Cardiology
Volume24
Issue number5
DOIs
StatePublished - Sep 1 2003

Fingerprint

Hydrops Fetalis
Amiodarone
Tachycardia
Digoxin
Edema
Fetus
Mothers
Procainamide
Therapeutics
Hypothyroidism
Exanthema
Propranolol

Keywords

  • Amiodarone
  • Fetal supraventricular tachyarrhythmias
  • Hydrops fetalis

Cite this

Role of amiodarone in the treatment of fetal supraventricular tachyarrhythmias and hydrops fetalis. / Khositseth, A.; Ramin, K. D.; O'Leary, P. W.; Porter, C. J.

In: Pediatric Cardiology, Vol. 24, No. 5, 01.09.2003, p. 454-456.

Research output: Contribution to journalArticle

Khositseth, A. ; Ramin, K. D. ; O'Leary, P. W. ; Porter, C. J. / Role of amiodarone in the treatment of fetal supraventricular tachyarrhythmias and hydrops fetalis. In: Pediatric Cardiology. 2003 ; Vol. 24, No. 5. pp. 454-456.
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