Robust methods with high efficiency, bonded-carbon HPLC columns

Elena Khmelnitskaia, Dwight Stoll, Peter W. Carr

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Loss of stationary phase, retention drift, and short column life are common problems using bonded-phase silicas, especially with aggressive mobile phases. A new bonding technology overcomes these problems by attaching C18 groups to a carbon surface with ultra-stable carbon-carbon bonds. This note shows that robust methods with high efficiency are now possible using ultra-stable bonded-carbon columns.

Original languageEnglish (US)
Number of pages1
JournalLC-GC North America
Issue number2 SUPPL.
StatePublished - Feb 1 2002


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