Robust control approach to force estimation in a constant position optical tweezers

Tanuj Aggarwal, Hullas Sehgal, Murti Salapaka

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Feedback enhanced optical tweezers with position regulation capability enable detection and estimation of forces in the pico-Newton regime. In this article we delineate the fundamental limitations and challenges of existing approaches for regulating position and force estimation in an optical tweezer. A modern control systems approach is shown to improve the bandwidth of force estimation by three to four times which is corroborated experimentally.

Original languageEnglish (US)
Article number115108
JournalReview of Scientific Instruments
Volume82
Issue number11
DOIs
StatePublished - Nov 2011

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