Rituximab-induced remission of a gastric MALT lymphoma

Yvonne H. Datta; Bal Kampalath; David G. Binion

doi:10.1080/1042819032000159889

Rituximab-induced remission of a gastric MALT lymphoma

Yvonne H. Datta, Bal Kampalath, David G. Binion

Medicine - Hematology, Oncology, Transplant

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Gastric MALT lymphoma is usually associated with H. pylori infection, and responds to treatment with antibiotics and a proton pump inhibitor. We report a case of H. pylori negative gastric MALT lymphoma. The patient was followed conservatively for 2 years until she developed gastrointestinal bleeding with significant anemia. She was treated with rituximab 375 mg/m² weekly for four doses, which resulted in a biopsy proven complete remission. Rituximab therapy is a reasonable, well tolerated treatment alternative for MALT lymphomas not associated with H. pylori.

Original language	English (US)
Pages (from-to)	1297-1299
Number of pages	3
Journal	Leukemia and Lymphoma
Volume	45
Issue number	6
DOIs	https://doi.org/10.1080/1042819032000159889
State	Published - Jun 2004

Keywords

Gastric
Lymphoma
MALT
Rituximab

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/1042819032000159889

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AU - Binion, David G.

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N2 - Gastric MALT lymphoma is usually associated with H. pylori infection, and responds to treatment with antibiotics and a proton pump inhibitor. We report a case of H. pylori negative gastric MALT lymphoma. The patient was followed conservatively for 2 years until she developed gastrointestinal bleeding with significant anemia. She was treated with rituximab 375 mg/m2 weekly for four doses, which resulted in a biopsy proven complete remission. Rituximab therapy is a reasonable, well tolerated treatment alternative for MALT lymphomas not associated with H. pylori.

AB - Gastric MALT lymphoma is usually associated with H. pylori infection, and responds to treatment with antibiotics and a proton pump inhibitor. We report a case of H. pylori negative gastric MALT lymphoma. The patient was followed conservatively for 2 years until she developed gastrointestinal bleeding with significant anemia. She was treated with rituximab 375 mg/m2 weekly for four doses, which resulted in a biopsy proven complete remission. Rituximab therapy is a reasonable, well tolerated treatment alternative for MALT lymphomas not associated with H. pylori.

KW - Gastric

KW - Lymphoma

KW - MALT

KW - Rituximab

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ER -

Rituximab-induced remission of a gastric MALT lymphoma

Abstract

Keywords

UN SDGs

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