TY - JOUR
T1 - Right heart failure after left ventricular assist device implantation
T2 - a persistent problem
AU - Siems, Chesney K
AU - Aggarwal, Rishav
AU - Shaffer, Andrew
AU - John, Ranjit
N1 - Publisher Copyright:
© 2023, Indian Association of Cardiovascular-Thoracic Surgeons.
PY - 2023
Y1 - 2023
N2 - Left ventricular assist device (LVAD) is an option for bridge-to-transplant or destination therapy for patients with end-stage heart failure. Right heart failure (RHF) remains a complication after LVAD implantation that portends high morbidity and mortality, despite advances in LVAD technology. Definitions of RHF vary, but generally include the need for inotropic or pulmonary vasodilator support, or potential right ventricular (RV) mechanical circulatory support. This review covers the complex pathophysiology of RHF related to underlying myocardial dysfunction, interventricular dependence, and RV afterload, as well as treatment strategies to curtail this challenging problem.
AB - Left ventricular assist device (LVAD) is an option for bridge-to-transplant or destination therapy for patients with end-stage heart failure. Right heart failure (RHF) remains a complication after LVAD implantation that portends high morbidity and mortality, despite advances in LVAD technology. Definitions of RHF vary, but generally include the need for inotropic or pulmonary vasodilator support, or potential right ventricular (RV) mechanical circulatory support. This review covers the complex pathophysiology of RHF related to underlying myocardial dysfunction, interventricular dependence, and RV afterload, as well as treatment strategies to curtail this challenging problem.
KW - Adult cardiac
KW - Left ventricular assist device
KW - Mechanical circulatory support
KW - Right heart failure
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U2 - 10.1007/s12055-023-01481-z
DO - 10.1007/s12055-023-01481-z
M3 - Review article
AN - SCOPUS:85148447530
SN - 0970-9134
JO - Indian Journal of Thoracic and Cardiovascular Surgery
JF - Indian Journal of Thoracic and Cardiovascular Surgery
ER -