Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis

Keyphrases

• Antibiotic Activity 33%
• Antibiotic Class 33%
• Antibiotics 100%
• Autoimmune Disease 33%
• Autoimmunity 100%
• Cellular Physiology 33%
• Cytokine Production 33%
• Effector Function 33%
• Electron Transport Chain 33%
• Elongation Factor 66%
• Experimental Autoimmune Encephalomyelitis 33%
• Host Cell 33%
• Linezolid 66%
• Mitochondrial Elongation 66%
• Mitochondrial Protein Synthesis 100%
• Mitochondrial Translation 33%
• Nicotinamide Adenine Dinucleotide (NAD+) 33%
• Oxidative Phosphorylation (OXPHOS) 33%
• Pathogenicity 33%
• T Cell Activation 33%
• T Cell Effector Function 100%
• T Cells 100%
• T Helper 17 (Th17) 33%
• T-cell Mediated 33%

Immunology and Microbiology

• Antimicrobial Activity 20%
• Antimicrobial Agent 20%
• Autoimmunity 100%
• Cell Function 40%
• Cytokine Production 20%
• Effector Cell 100%
• Elongation Factor 40%
• Experimental Autoimmune Encephalomyelitis 20%
• Immunosuppressive Drug 20%
• In Vitro 20%
• Oxidative Phosphorylation 20%
• Pathogenicity 20%
• Protein Synthesis 100%
• Respiratory Chain 20%
• T Cell 100%
• T Cell-Mediated Autoimmune Disease 20%
• T Helper 17 Cell 20%