Abstract
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children. Recent work presented in this issue of Cancer Cell by Fleischmann et al. on gene knockout mice revealed a remarkable molecular pathway for rhabdomyosarcomagenesis, in which Trp53/Fos double mutant mice developed RMS of the facial and orbital regions with high penetrance. This finding may provide novel molecular mechanisms for Rhabdomyosarcomagenesis and therapeutic implications for RMS patients.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 421-422 |
| Number of pages | 2 |
| Journal | Cancer Cell |
| Volume | 4 |
| Issue number | 6 |
| DOIs | |
| State | Published - Dec 2003 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
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