Rhabdomyosarcoma with heterologous cartilage of the uterine cervix: A clinicopathologic and immunohistochemical study of an aggressive neoplasm in a young female

Theresa Perrone, Linda F. Carson, Louis P. Dehner

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28 Scopus citations

Abstract

This report concerns a 20‐year‐old female who had a F.I.G.O. stage I rhabdomyosarcoma (sarcoma botryoides) of the cervix with a predominant embryonal pattern and heterologous cartilage that pursued an aggressive course despite surgery and chemotherapy. The patient had a pelvic recurrence, developed pulmonary metastases 15 months after diagnosis, and died 6 months later. Despite some previously published favorable prognostic assessments about this unique variant of cervical rhabdomyosarcoma, our limited experience would interject a note of caution, especially in the presence of a focal alveolar pattern and invasion of lymphatics in the cervix.

Original languageEnglish (US)
Pages (from-to)72-76
Number of pages5
JournalMedical and Pediatric Oncology
Volume18
Issue number1
DOIs
StatePublished - 1990

Keywords

  • alveolar rhabdomyosarcoma
  • embryonal rhabdomyosarcoma
  • sarcoma botryoides
  • uterine cervix neoplasms

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