Revisiting Trypanosome Mitochondrial Genome Mysteries

Broader and Deeper

Research output: Contribution to journalShort survey

1 Citation (Scopus)

Abstract

What do the products of a genome do, and when and why are they needed? For the protein products of the trypanosomatid parasites’ mitochondrial genomes, the total expressed protein repertoire and the identities of the more difficult-to-characterize products have been challenging to acquire. Comparative genomics and new technologies may resolve that.

Original languageEnglish (US)
Pages (from-to)102-104
Number of pages3
JournalTrends in Parasitology
Volume35
Issue number2
DOIs
StatePublished - Feb 1 2019
Externally publishedYes

Fingerprint

Mitochondrial Genome
Trypanosomiasis
Genomics
Parasites
Proteins
Genome
Technology

Keywords

  • NADH dehydrogenase
  • RNA editing
  • electron transport chain
  • kinetoplastid
  • maxicircle
  • mitochondrial ribosome

PubMed: MeSH publication types

  • Journal Article
  • Review

Cite this

Revisiting Trypanosome Mitochondrial Genome Mysteries : Broader and Deeper. / Zimmer, Sara L.

In: Trends in Parasitology, Vol. 35, No. 2, 01.02.2019, p. 102-104.

Research output: Contribution to journalShort survey

@article{d193927e7e6445fbba4454df043a23ee,
title = "Revisiting Trypanosome Mitochondrial Genome Mysteries: Broader and Deeper",
abstract = "What do the products of a genome do, and when and why are they needed? For the protein products of the trypanosomatid parasites’ mitochondrial genomes, the total expressed protein repertoire and the identities of the more difficult-to-characterize products have been challenging to acquire. Comparative genomics and new technologies may resolve that.",
keywords = "NADH dehydrogenase, RNA editing, electron transport chain, kinetoplastid, maxicircle, mitochondrial ribosome",
author = "Zimmer, {Sara L}",
year = "2019",
month = "2",
day = "1",
doi = "10.1016/j.pt.2018.09.006",
language = "English (US)",
volume = "35",
pages = "102--104",
journal = "Trends in Parasitology",
issn = "1471-4922",
publisher = "Elsevier Limited",
number = "2",

}

TY - JOUR

T1 - Revisiting Trypanosome Mitochondrial Genome Mysteries

T2 - Broader and Deeper

AU - Zimmer, Sara L

PY - 2019/2/1

Y1 - 2019/2/1

N2 - What do the products of a genome do, and when and why are they needed? For the protein products of the trypanosomatid parasites’ mitochondrial genomes, the total expressed protein repertoire and the identities of the more difficult-to-characterize products have been challenging to acquire. Comparative genomics and new technologies may resolve that.

AB - What do the products of a genome do, and when and why are they needed? For the protein products of the trypanosomatid parasites’ mitochondrial genomes, the total expressed protein repertoire and the identities of the more difficult-to-characterize products have been challenging to acquire. Comparative genomics and new technologies may resolve that.

KW - NADH dehydrogenase

KW - RNA editing

KW - electron transport chain

KW - kinetoplastid

KW - maxicircle

KW - mitochondrial ribosome

UR - http://www.scopus.com/inward/record.url?scp=85054449265&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85054449265&partnerID=8YFLogxK

U2 - 10.1016/j.pt.2018.09.006

DO - 10.1016/j.pt.2018.09.006

M3 - Short survey

VL - 35

SP - 102

EP - 104

JO - Trends in Parasitology

JF - Trends in Parasitology

SN - 1471-4922

IS - 2

ER -