Reversible regulation of bioactive ligands presented on immobilized gold nanoparticles

Xintong Wang, Jeremiah J. Riesberg, Wei Shen

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

A polypeptide fusion of a bioactive ligand and a coiled-coil A was functionalized on gold nanoparticles, which were subsequently immobilized on substrates. The accessibility of the ligand could be reversibly controlled via co-immobilization and removal of B-poly(ethylene) glycol through heterodimerization between A and the complementary coiled-coil B.

Original languageEnglish (US)
Pages (from-to)2812-2815
Number of pages4
JournalSoft Matter
Volume8
Issue number10
DOIs
StatePublished - Mar 14 2012

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