Reversible Cortical Blindness (Anton's Syndrome) Associated with Bilateral Occipital EEG Abnormalities

Karen L. Roos, P. J. Tuite, M. E. Below, R. M. Pascuzzi

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


A 50 year-old woman with systemic lupus erythematosus was admitted in an obtunded state. An EEG recorded while she was unconscious demonstrated one episode of rhythmic sharp wave activity in the left occipital area that lasted for 5 minutes and was followed later in thesame recording by an episodeof high amplitude sharp wave discharges in the right posterior temporal and occipital areas. When the patient regained consciousness, she had an Anton's syndrome of cortical blindness with denial. When she recovered light perception only, the EEG demonstrated synchronous and independent right and left occipital-posterior temporal periodic lateralized epileptiform discharges (PLEDs). Cortical blindness (Anton's syndrome) associated with abnormal electrical activity in the occipital areas has only rarely been reported. Our case is significant for the following reasons: 1) PLEDs maximal right and left occipital areas associated with bilateral visual loss has not previously been observed; 2) abnormal electrical activity in the occipital lobes may be a reversible cause of Anton's syndrome.

Original languageEnglish (US)
Pages (from-to)104-109
Number of pages6
JournalClinical EEG and Neuroscience
Issue number2
StatePublished - Apr 1990


  • Anton's Syndrome
  • Cortical Blindness
  • Electroencephalography
  • Occipital PLEDs
  • Systemic Lupus Erythematosus


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