Retrovirus vectors

P. Lech; N. Somia

doi:10.1159/000125574

Retrovirus vectors

P. Lech, N. Somia

Research output: Chapter in Book/Report/Conference proceeding › Chapter

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Abstract

In this chapter, we present an outline of retroviruses and retroviral vectors - the concepts and applications. In particular, we discuss lentiviral vectors and the suitability of these vectors for the treatment of renal pathologies. We review vector design and the data on the use of lentiviral vectors for gene transfer to the kidney. Finally, we discuss potential pathologies and avenues for the optimization of the technology for gene transfer to a complex organ such as the kidney.

Original language	English (US)
Title of host publication	Gene Therapy for Renal Diseases and Transplantation
Editors	Ariela Benigni, Remuzzi Giuseppe
Pages	30-46
Number of pages	17
DOIs	https://doi.org/10.1159/000125574
State	Published - 2008

Publication series

Name	Contributions to Nephrology
Volume	159
ISSN (Print)	0302-5144

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Copyright 2008 Elsevier B.V., All rights reserved.

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10.1159/000125574

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title = "Retrovirus vectors",

abstract = "In this chapter, we present an outline of retroviruses and retroviral vectors - the concepts and applications. In particular, we discuss lentiviral vectors and the suitability of these vectors for the treatment of renal pathologies. We review vector design and the data on the use of lentiviral vectors for gene transfer to the kidney. Finally, we discuss potential pathologies and avenues for the optimization of the technology for gene transfer to a complex organ such as the kidney.",

author = "P. Lech and N. Somia",

year = "2008",

doi = "10.1159/000125574",

language = "English (US)",

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series = "Contributions to Nephrology",

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editor = "Ariela Benigni and Remuzzi Giuseppe",

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AU - Somia, N.

PY - 2008

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AB - In this chapter, we present an outline of retroviruses and retroviral vectors - the concepts and applications. In particular, we discuss lentiviral vectors and the suitability of these vectors for the treatment of renal pathologies. We review vector design and the data on the use of lentiviral vectors for gene transfer to the kidney. Finally, we discuss potential pathologies and avenues for the optimization of the technology for gene transfer to a complex organ such as the kidney.

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UR - http://www.scopus.com/inward/citedby.url?scp=48549096125&partnerID=8YFLogxK

U2 - 10.1159/000125574

DO - 10.1159/000125574

M3 - Chapter

C2 - 18391583

AN - SCOPUS:48549096125

SN - 9783805585057

T3 - Contributions to Nephrology

SP - 30

EP - 46

BT - Gene Therapy for Renal Diseases and Transplantation

A2 - Benigni, Ariela

A2 - Giuseppe, Remuzzi

ER -

Retrovirus vectors

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