Retrovirus vectors

P. Lech, N. Somia

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Abstract

In this chapter, we present an outline of retroviruses and retroviral vectors - the concepts and applications. In particular, we discuss lentiviral vectors and the suitability of these vectors for the treatment of renal pathologies. We review vector design and the data on the use of lentiviral vectors for gene transfer to the kidney. Finally, we discuss potential pathologies and avenues for the optimization of the technology for gene transfer to a complex organ such as the kidney.

Original languageEnglish (US)
Title of host publicationGene Therapy for Renal Diseases and Transplantation
EditorsAriela Benigni, Remuzzi Giuseppe
Pages30-46
Number of pages17
DOIs
StatePublished - Aug 20 2008

Publication series

NameContributions to Nephrology
Volume159
ISSN (Print)0302-5144

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