Retroviral vector targeting to human immunodeficiency virus type 1- infected cells by receptor pseudotyping

Nikunj V. Somia; Hiroyuki Miyoshi; Mark J. Schmitt; Inder M. Verma

doi:10.1128/JVI.74.9.4420-4424.2000

Retroviral vector targeting to human immunodeficiency virus type 1- infected cells by receptor pseudotyping

Nikunj V. Somia, Hiroyuki Miyoshi, Mark J. Schmitt, Inder M. Verma

Genetics, Cell Biology and Development (TMED)

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

We report the generation of retroviral vectors based on Moloney murine leukemia virus that specifically transduce cells infected with T-cell-tropic human immunodeficiency virus type 1 (HIV-1). This vector was pseudotyped with T-cell-tropic HIV-1 receptors CD4 and CXCR4. We demonstrate that transduction is contingent upon HIV-1 gp120 and gp41 expression.

Original language	English (US)
Pages (from-to)	4420-4424
Number of pages	5
Journal	Journal of virology
Volume	74
Issue number	9
DOIs	https://doi.org/10.1128/JVI.74.9.4420-4424.2000
State	Published - 2000

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Publisher link

10.1128/JVI.74.9.4420-4424.2000

Find It

Find It at U of M Libraries

Cite this

@article{cdf95d08c4794fbd88f345412c4e78b0,

title = "Retroviral vector targeting to human immunodeficiency virus type 1- infected cells by receptor pseudotyping",

abstract = "We report the generation of retroviral vectors based on Moloney murine leukemia virus that specifically transduce cells infected with T-cell-tropic human immunodeficiency virus type 1 (HIV-1). This vector was pseudotyped with T-cell-tropic HIV-1 receptors CD4 and CXCR4. We demonstrate that transduction is contingent upon HIV-1 gp120 and gp41 expression.",

author = "Somia, {Nikunj V.} and Hiroyuki Miyoshi and Schmitt, {Mark J.} and Verma, {Inder M.}",

year = "2000",

doi = "10.1128/JVI.74.9.4420-4424.2000",

language = "English (US)",

volume = "74",

pages = "4420--4424",

journal = "Journal of virology",

issn = "0022-538X",

publisher = "American Society for Microbiology",

number = "9",

}

TY - JOUR

T1 - Retroviral vector targeting to human immunodeficiency virus type 1- infected cells by receptor pseudotyping

AU - Somia, Nikunj V.

AU - Miyoshi, Hiroyuki

AU - Schmitt, Mark J.

AU - Verma, Inder M.

PY - 2000

Y1 - 2000

N2 - We report the generation of retroviral vectors based on Moloney murine leukemia virus that specifically transduce cells infected with T-cell-tropic human immunodeficiency virus type 1 (HIV-1). This vector was pseudotyped with T-cell-tropic HIV-1 receptors CD4 and CXCR4. We demonstrate that transduction is contingent upon HIV-1 gp120 and gp41 expression.

AB - We report the generation of retroviral vectors based on Moloney murine leukemia virus that specifically transduce cells infected with T-cell-tropic human immunodeficiency virus type 1 (HIV-1). This vector was pseudotyped with T-cell-tropic HIV-1 receptors CD4 and CXCR4. We demonstrate that transduction is contingent upon HIV-1 gp120 and gp41 expression.

UR - http://www.scopus.com/inward/record.url?scp=0033993960&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033993960&partnerID=8YFLogxK

U2 - 10.1128/JVI.74.9.4420-4424.2000

DO - 10.1128/JVI.74.9.4420-4424.2000

M3 - Article

C2 - 10756057

AN - SCOPUS:0033993960

SN - 0022-538X

VL - 74

SP - 4420

EP - 4424

JO - Journal of virology

JF - Journal of virology

IS - 9

ER -

Retroviral vector targeting to human immunodeficiency virus type 1- infected cells by receptor pseudotyping

Abstract

UN SDGs

Publisher link

Find It

Other files and links

Fingerprint

Cite this