Results of an fetal alcohol spectrum disorders screening tool are associated with neuropsychological and behavioral measures

the CIFASD

doi:10.1111/acer.15133

Results of an fetal alcohol spectrum disorders screening tool are associated with neuropsychological and behavioral measures

the CIFASD

Psychiatry & Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: This study assessed whether the outcome of a screening tool for fetal alcohol spectrum disorders (FASD), the FASD-Tree, was associated with neuropsychological and behavioral outcomes. Methods: Data for this study were collected as part of the fourth phase of the Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD-4). Participants (N = 175, 5 to 16 years) with or without histories of prenatal alcohol exposure were recruited from San Diego and Minneapolis. Each participant was screened using the FASD-Tree and administered a neuropsychological test battery; parents or guardians completed behavioral questionnaires. The FASD-Tree incorporates physical and behavioral measures and provides an outcome regarding the presence of FASD (FASD-Positive or FASD-Negative). Logistic regression was used to test whether the FASD-Tree outcome was associated with general cognitive ability, executive function, academic achievement, and behavior. Associations were tested in two groups: the whole sample and only correctly classified participants. Results: Results of the FASD-Tree were associated with neuropsychological and behavioral measures. Participants classified as FASD-Positive were more likely than those classified as FASD-Negative to have a lower IQ score and exhibit poorer performance on measures of executive and academic functions. Behaviorally, participants classified as FASD-Positive were rated as having more behavior problems and adaptive difficulties. Similar relationships were found for all measures when including only participants correctly classified by the FASD-Tree screening tool. Conclusion: Results from the FASD-Tree screening tool were associated with neuropsychological and behavioral measures. Participants classified as FASD-Positive were more likely to have impairment in all domains tested. The results support the effectiveness of the FASD-Tree as a screening tool for use in clinical settings, providing an efficient and accurate way to identify patients in need of additional evaluation.

Original language	English (US)
Journal	Alcoholism: Clinical and Experimental Research
DOIs	https://doi.org/10.1111/acer.15133
State	Accepted/In press - 2023

Bibliographical note

Funding Information:
The authors thank the families who graciously participate in our studies. All or part of this work was done in conjunction with the CIFASD, which is funded by grants from the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Additional information about CIFASD, including data‐sharing opportunities, can be found at www.cifasd.org . Research described in this paper was supported by NIAAA grant number U01 AA014834. Additional support was provided by U24 AA014811, U24 AA014815, U01 AA026102, T32 AA013525.

Publisher Copyright:
© 2023 The Authors. Alcohol: Clinical and Experimental Research published by Wiley Periodicals LLC on behalf of Research Society on Alcohol.

Keywords

behavior
diagnosis
fetal alcohol spectrum disorders
neuropsychological assessment
prenatal alcohol exposure
screening tool

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Publisher link

10.1111/acer.15133

Cite this

@article{b9240956368d4c798876a676b2601b63,

title = "Results of an fetal alcohol spectrum disorders screening tool are associated with neuropsychological and behavioral measures",

abstract = "Purpose: This study assessed whether the outcome of a screening tool for fetal alcohol spectrum disorders (FASD), the FASD-Tree, was associated with neuropsychological and behavioral outcomes. Methods: Data for this study were collected as part of the fourth phase of the Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD-4). Participants (N = 175, 5 to 16 years) with or without histories of prenatal alcohol exposure were recruited from San Diego and Minneapolis. Each participant was screened using the FASD-Tree and administered a neuropsychological test battery; parents or guardians completed behavioral questionnaires. The FASD-Tree incorporates physical and behavioral measures and provides an outcome regarding the presence of FASD (FASD-Positive or FASD-Negative). Logistic regression was used to test whether the FASD-Tree outcome was associated with general cognitive ability, executive function, academic achievement, and behavior. Associations were tested in two groups: the whole sample and only correctly classified participants. Results: Results of the FASD-Tree were associated with neuropsychological and behavioral measures. Participants classified as FASD-Positive were more likely than those classified as FASD-Negative to have a lower IQ score and exhibit poorer performance on measures of executive and academic functions. Behaviorally, participants classified as FASD-Positive were rated as having more behavior problems and adaptive difficulties. Similar relationships were found for all measures when including only participants correctly classified by the FASD-Tree screening tool. Conclusion: Results from the FASD-Tree screening tool were associated with neuropsychological and behavioral measures. Participants classified as FASD-Positive were more likely to have impairment in all domains tested. The results support the effectiveness of the FASD-Tree as a screening tool for use in clinical settings, providing an efficient and accurate way to identify patients in need of additional evaluation.",

keywords = "behavior, diagnosis, fetal alcohol spectrum disorders, neuropsychological assessment, prenatal alcohol exposure, screening tool",

author = "{the CIFASD} and Hyland, {Matthew T.} and Courchesne-Krak, {Natasia S.} and Bernes, {Gemma A.} and Wozniak, {Jeffrey R.} and Jones, {Kenneth L.} and Miguel Del Campo and Riley, {Edward P.} and Mattson, {Sarah N.}",

note = "Funding Information: The authors thank the families who graciously participate in our studies. All or part of this work was done in conjunction with the CIFASD, which is funded by grants from the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Additional information about CIFASD, including data‐sharing opportunities, can be found at www.cifasd.org . Research described in this paper was supported by NIAAA grant number U01 AA014834. Additional support was provided by U24 AA014811, U24 AA014815, U01 AA026102, T32 AA013525. Publisher Copyright: {\textcopyright} 2023 The Authors. Alcohol: Clinical and Experimental Research published by Wiley Periodicals LLC on behalf of Research Society on Alcohol.",

year = "2023",

doi = "10.1111/acer.15133",

language = "English (US)",

journal = "Alcoholism: Clinical and Experimental Research",

issn = "0145-6008",

publisher = "Wiley-Blackwell",

}

TY - JOUR

T1 - Results of an fetal alcohol spectrum disorders screening tool are associated with neuropsychological and behavioral measures

AU - the CIFASD

AU - Hyland, Matthew T.

AU - Courchesne-Krak, Natasia S.

AU - Bernes, Gemma A.

AU - Wozniak, Jeffrey R.

AU - Jones, Kenneth L.

AU - Del Campo, Miguel

AU - Riley, Edward P.

AU - Mattson, Sarah N.

N1 - Funding Information: The authors thank the families who graciously participate in our studies. All or part of this work was done in conjunction with the CIFASD, which is funded by grants from the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Additional information about CIFASD, including data‐sharing opportunities, can be found at www.cifasd.org . Research described in this paper was supported by NIAAA grant number U01 AA014834. Additional support was provided by U24 AA014811, U24 AA014815, U01 AA026102, T32 AA013525. Publisher Copyright: © 2023 The Authors. Alcohol: Clinical and Experimental Research published by Wiley Periodicals LLC on behalf of Research Society on Alcohol.

PY - 2023

Y1 - 2023

N2 - Purpose: This study assessed whether the outcome of a screening tool for fetal alcohol spectrum disorders (FASD), the FASD-Tree, was associated with neuropsychological and behavioral outcomes. Methods: Data for this study were collected as part of the fourth phase of the Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD-4). Participants (N = 175, 5 to 16 years) with or without histories of prenatal alcohol exposure were recruited from San Diego and Minneapolis. Each participant was screened using the FASD-Tree and administered a neuropsychological test battery; parents or guardians completed behavioral questionnaires. The FASD-Tree incorporates physical and behavioral measures and provides an outcome regarding the presence of FASD (FASD-Positive or FASD-Negative). Logistic regression was used to test whether the FASD-Tree outcome was associated with general cognitive ability, executive function, academic achievement, and behavior. Associations were tested in two groups: the whole sample and only correctly classified participants. Results: Results of the FASD-Tree were associated with neuropsychological and behavioral measures. Participants classified as FASD-Positive were more likely than those classified as FASD-Negative to have a lower IQ score and exhibit poorer performance on measures of executive and academic functions. Behaviorally, participants classified as FASD-Positive were rated as having more behavior problems and adaptive difficulties. Similar relationships were found for all measures when including only participants correctly classified by the FASD-Tree screening tool. Conclusion: Results from the FASD-Tree screening tool were associated with neuropsychological and behavioral measures. Participants classified as FASD-Positive were more likely to have impairment in all domains tested. The results support the effectiveness of the FASD-Tree as a screening tool for use in clinical settings, providing an efficient and accurate way to identify patients in need of additional evaluation.

AB - Purpose: This study assessed whether the outcome of a screening tool for fetal alcohol spectrum disorders (FASD), the FASD-Tree, was associated with neuropsychological and behavioral outcomes. Methods: Data for this study were collected as part of the fourth phase of the Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD-4). Participants (N = 175, 5 to 16 years) with or without histories of prenatal alcohol exposure were recruited from San Diego and Minneapolis. Each participant was screened using the FASD-Tree and administered a neuropsychological test battery; parents or guardians completed behavioral questionnaires. The FASD-Tree incorporates physical and behavioral measures and provides an outcome regarding the presence of FASD (FASD-Positive or FASD-Negative). Logistic regression was used to test whether the FASD-Tree outcome was associated with general cognitive ability, executive function, academic achievement, and behavior. Associations were tested in two groups: the whole sample and only correctly classified participants. Results: Results of the FASD-Tree were associated with neuropsychological and behavioral measures. Participants classified as FASD-Positive were more likely than those classified as FASD-Negative to have a lower IQ score and exhibit poorer performance on measures of executive and academic functions. Behaviorally, participants classified as FASD-Positive were rated as having more behavior problems and adaptive difficulties. Similar relationships were found for all measures when including only participants correctly classified by the FASD-Tree screening tool. Conclusion: Results from the FASD-Tree screening tool were associated with neuropsychological and behavioral measures. Participants classified as FASD-Positive were more likely to have impairment in all domains tested. The results support the effectiveness of the FASD-Tree as a screening tool for use in clinical settings, providing an efficient and accurate way to identify patients in need of additional evaluation.

KW - behavior

KW - diagnosis

KW - fetal alcohol spectrum disorders

KW - neuropsychological assessment

KW - prenatal alcohol exposure

KW - screening tool

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U2 - 10.1111/acer.15133

DO - 10.1111/acer.15133

M3 - Article

C2 - 37328959

AN - SCOPUS:85164135846

SN - 0145-6008

JO - Alcoholism: Clinical and Experimental Research

JF - Alcoholism: Clinical and Experimental Research

ER -

Results of an fetal alcohol spectrum disorders screening tool are associated with neuropsychological and behavioral measures

Abstract

Bibliographical note

Keywords

UN SDGs

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