Results of a nation-wide survey evaluating psychotropic medication use in fragile X syndrome

Maria G. Valdovinos, Rahul A. Parsa, Michelle L. Alexander

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Fragile X syndrome (FXS) is the most common inherited cause of mental retardation. The behavioral phenotype associated with FXS includes hyperactivity, anxiety, and sometimes problem behaviors for which stimulants, antipsychotics, and SSRI antidepressants are prescribed. Little information, however, is known about the side effects individuals with FXS may experience as a result of taking these medications. Using a nation-wide survey, this study examined the prescription patterns of psychotropic medication use within the FXS population and the prevalence of side effects associated with psychotropic medication use by people diagnosed with FXS. Significant associations were found between the most commonly prescribed medications and side effects for our total sample. These findings give insight to the different dimensions of medication use in people diagnosed with FXS.

Original languageEnglish (US)
Pages (from-to)23-37
Number of pages15
JournalJournal of Developmental and Physical Disabilities
Issue number1
StatePublished - Feb 2009
Externally publishedYes


  • Fragile X syndrome
  • Psychotropic medication
  • Side effects


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