Restricted spatial models for the analysis of geographic and racial disparities in the incidence of low birthweight in Pennsylvania

Guangzi Song, Loni Philip Tabb, Harrison Quick

Research output: Contribution to journalArticlepeer-review

Abstract

The incidence of low birthweight is a common measure of public health due to the increased risk of complications associated with infants having low and very low birthweights. Moreover, many factors that increase the risk of an infant having a low birthweight can be linked to the mother's socioeconomic status, leading to large racial/ethnic disparities in its incidence. Our objective is thus to analyze the incidence of low and very low birthweight in Pennsylvania counties by race/ethnicity. Due to the small number of births in many Pennsylvania counties when stratified by race/ethnicity, our methods must walk a fine line: While we wish to leverage spatial structure to improve the precision of our estimates, we also wish to avoid oversmoothing the data, which can yield spurious conclusions. As such, we develop a framework by which we can measure (and control) the informativeness of our spatial model. To analyze the data, we first model the Pennsylvania birth data using the conditional autoregressive model to demonstrate the extent to which it can lead to oversmoothing. We then reanalyze the data using our proposed framework and highlight its ability to detect (or not detect) evidence of racial/ethnic disparities in the incidence of low birthweight.

Original languageEnglish (US)
Article number100649
JournalSpatial and Spatio-temporal Epidemiology
Volume49
DOIs
StatePublished - Jun 2024

Bibliographical note

Publisher Copyright:
© 2024 Elsevier Ltd

Keywords

  • Bayesian inference
  • CAR model
  • Health disparities
  • Small area estimation

PubMed: MeSH publication types

  • Journal Article

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