Two improvements in propranolol resolution were developed. Both the (+)‐ and (‐)‐di‐(p‐toluoyl)tartaric acids were used as the resolving agents. This procedure reduced the number of crystallizations needed to obtain a pure product. Furthermore, synthesis of the resolving agent was improved.
- Enantiomers—propranolol, resolving agents
- Propranolol—racemic mixtures, resolution of enantiomers,.(+)‐ and (‐)‐di‐(p‐toluoyl)tartaric acids used as resolving agents