Abstract
Two improvements in propranolol resolution were developed. Both the (+)‐ and (‐)‐di‐(p‐toluoyl)tartaric acids were used as the resolving agents. This procedure reduced the number of crystallizations needed to obtain a pure product. Furthermore, synthesis of the resolving agent was improved.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1181-1182 |
| Number of pages | 2 |
| Journal | Journal of Pharmaceutical Sciences |
| Volume | 68 |
| Issue number | 9 |
| DOIs | |
| State | Published - Sep 1979 |
Keywords
- Enantiomers—propranolol, resolving agents
- Propranolol—racemic mixtures, resolution of enantiomers,.(+)‐ and (‐)‐di‐(p‐toluoyl)tartaric acids used as resolving agents