Resection of colorectal liver metastases: Current perspectives

James M. McLoughlin, Eric H. Jensen, Mokenge Malafa

Research output: Contribution to journalReview articlepeer-review

66 Scopus citations


Background: Metastases to the liver is the leading cause of death in patients with colorectal cancer. Methods: The authors review the data on diagnosis and management of this clinical problem, and they discuss management options that can be considered. Results: Complete surgical resection of metastases from colorectal cancer that are localized to the liver results in 5-year survival rates ranging from 26% to 40%. Conclusions: By adding modalities such as targeted systemic therapy and other "local" treatments for liver metastases, further gains in survival are anticipated.

Original languageEnglish (US)
Pages (from-to)32-41
Number of pages10
JournalCancer Control
Issue number1
StatePublished - Jan 2006
Externally publishedYes


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