Abstract
The pathophysiology of Chiari-related symptoms and syringomyelia remains enigmatic. Present-day technology, most notably MR imaging, is providing progressively more sophisticated opportunities to test traditional as well as contemporary theories while adding to conventional animal models a selection of promising mechanical and computational representations of syringomyelia and its etiologies. We will briefly touch on the past and present of Chiari-related syringomyelia research with emphasis on essential questions related to the development of not just the anatomical anomalies but also the constellation of symptoms with which they are associated.
Original language | English (US) |
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Title of host publication | The Chiari Malformations |
Publisher | Springer New York |
Pages | 171-180 |
Number of pages | 10 |
Volume | 9781461463696 |
ISBN (Electronic) | 9781461463696 |
ISBN (Print) | 1461463688, 9781461463689 |
DOIs | |
State | Published - Mar 1 2013 |
Externally published | Yes |
Keywords
- CSF flow
- CSF hydrodynamics
- Cine MRI
- Computational fluid dynamics
- Flow jets
- Foramen magnum
- Syringomyelia theories