Reperfusion therapy for acute myocardial infarction in the elderly

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Abstract

While elderly patients (aged ≥ 75 years) represent a small segment of the general population, they account for disproportionate morbidity and mortality associated with acute myocardial infarction. Consequently, the efficacy and utilization of reperfusion therapy - thrombolysis and primary coronary angioplasty/stenting - remain highly relevant. A randomized clinical trial of thrombolysis in the elderly has never been performed, although subgroup analyses have suggested a benefit. The effectiveness of thrombolysis in the elderly has been challenged by observational studies documenting unexpectedly high mortality. The efficacy of primary coronary angioplasty/stenting is now well established and growing evidence suggests this approach is superior to thrombolysis in the elderly.

Original languageEnglish (US)
Pages (from-to)40-43
Number of pages4
JournalGeriatrics and Aging
Volume6
Issue number8
StatePublished - Sep 1 2003

Keywords

  • Acute myocardial infarction
  • Geriatrics
  • Guidelines
  • Primary coronary angioplasty
  • Thrombolysis

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