While elderly patients (aged ≥ 75 years) represent a small segment of the general population, they account for disproportionate morbidity and mortality associated with acute myocardial infarction. Consequently, the efficacy and utilization of reperfusion therapy - thrombolysis and primary coronary angioplasty/stenting - remain highly relevant. A randomized clinical trial of thrombolysis in the elderly has never been performed, although subgroup analyses have suggested a benefit. The effectiveness of thrombolysis in the elderly has been challenged by observational studies documenting unexpectedly high mortality. The efficacy of primary coronary angioplasty/stenting is now well established and growing evidence suggests this approach is superior to thrombolysis in the elderly.
|Original language||English (US)|
|Number of pages||4|
|Journal||Geriatrics and Aging|
|State||Published - Sep 1 2003|
- Acute myocardial infarction
- Primary coronary angioplasty