Repeat-induced point mutation (RIP) in crosses with wild-isolated strains of Neurospora crassa: Evidence for dominant reduction of RIP

Felicite Kamdem Noubissi, Kevin McCluskey, Durgadas P. Kasbekar

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Seventy-one wild-isolated strains of Neurospora crassa were examined for their ability to support repeat-induced point mutation (RIP) in the erg-3 locus. RIP was exceptionally inefficient but detectable in crosses with the strain FGSC 430 from Adiopodoume, Ivory Coast. We could find no consistent differences in ascospore yields when wild isolates identified as "low-RIP" or "high-RIP" strains were crossed with strains bearing the segmental duplication Dp(IIIR > [I; II])AR17. This suggested that RiP may not be responsible for the barren phenotype of crosses involving segmental duplication strains.

Original languageEnglish (US)
Pages (from-to)91-97
Number of pages7
JournalFungal Genetics and Biology
Volume31
Issue number2
DOIs
StatePublished - Jan 1 2000

Keywords

  • Barren phenotype
  • Dominant suppression
  • Dow
  • RIP
  • Segmental aneuploidy
  • erg-3

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