Abstract
Alport syndrome is an inherited disorder of basement membrane collagen IV that frequently results in end-stage renal disease. Patients with Alport syndrome who undergo renal transplantation have generally excellent outcomes. Posttransplant antiglomerular basement membrane nephritis is a rare complication of renal transplantation for Alport syndrome. Because Alport syndrome is a genetic disorder, potential related donors must be carefully evaluated in order to minimize harm.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 267-270 |
| Number of pages | 4 |
| Journal | International Journal of Nephrology and Renovascular Disease |
| Volume | 11 |
| DOIs | |
| State | Published - 2018 |
Bibliographical note
Funding Information:NCT00481130), which receives financial support from the Alport Syndrome Foundation (alportsyndrome.org) and the Schuman and Pedersen families. Dr Kashtan is a site investigator for the CARDINAL trial (NCT03019185) sponsored by Reata Pharmaceuticals, Inc. and the HERA trial (NCT02855268) sponsored by Regulus Therapeutics, Inc. Dr Kashtan has also recently received research support from the Novartis Institute for Biomedical Research (NCT03074357).
Publisher Copyright:
© 2018 Kashtan.
Keywords
- Alport syndrome
- Collagen IV
- Kidney transplantation
- Posttransplant anti-GBM Nephritis