Renal Ischemia and Functional Outcomes Following Partial Nephrectomy

Joseph R. Zabell, Jitao Wu, Chalairat Suk-Ouichai, Steven C. Campbell

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations

Abstract

Renal function after renal cancer surgery is a critical component of survivorship. Quantity and quality of preserved parenchyma are the most important determinants of functional recovery; type and duration of ischemia play secondary roles. Several studies evaluated surgical techniques to minimize ischemia; however, long-term outcomes and potential benefits over clamped partial nephrectomy (PN) have not been consistently demonstrated. Analysis of acute kidney injury (AKI) after PN suggest that most kidneys recover strongly even if AKI is experienced after surgery. Ongoing study is required to evaluate long-term implications of AKI after PN and further assess impact of ischemia on functional outcomes.

Original languageEnglish (US)
Pages (from-to)243-255
Number of pages13
JournalUrologic Clinics of North America
Volume44
Issue number2
DOIs
StatePublished - May 2017

Keywords

  • Functional recovery
  • Ischemia
  • Partial nephrectomy
  • Radical nephrectomy
  • Renal cell carcinoma

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