Remote control of therapeutic T cells through a small molecule-gated chimeric receptor

Keyphrases

• T Cells 100%
• Small Molecules 100%
• Chimeric Antigen Receptor T Cells (CAR-T) 100%
• Remote Control 100%
• Tumor Cells 33%
• Cell Therapy 33%
• Therapeutic Agents 33%
• T Cell Activation 33%
• Engineered T Cells 33%
• Chemical Tools 33%
• Intracellular Signaling 33%
• Pharmacologic 33%
• Specific Antigen 33%
• Signal Component 33%
• Antigen Binding 33%
• User Control 33%
• Titratable 33%
• Severe Toxicity 33%
• Antigen Specificity 33%
• Therapeutic Cells 33%
• Excessive Exercise 33%
• Cellular Engineering 33%
• Engineered Cells 33%
• Therapeutic Function 33%

Biochemistry, Genetics and Molecular Biology

• Small Molecule 100%
• T Cell 100%
• Antigen Specificity 50%
• Chimeric Antigen Receptor 50%
• Antigen Binding 25%
• Intracellular Signaling 25%
• Cell Engineering 25%
• Cell Activity 25%

Chemistry

• Antigen 100%
• Cell Activity 20%